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Keto-5

Specialty Supplements | In stock | lb
x $26.35 = $26.35

Keto-5 helps the body burn fat effectively by entering the body into the ketosis metabolic state. Usually, the body uses glycogen stores as its fuel source and stores fat cells through lipogenesis. 


During the process of ketosis, fat cells are used as the source to fuel the body. Thus, burning fat cells in the process.


Ingredients: Keto Blend (Raspberry Ketone, Green Tea, Caffeine Anhydrous, Green Coffee Bean, Garcinia Cambogia (fruit), Cellulose (Vegetable Capsule).

Manufacturer Country: USA

Product Amount: 60 caps

Gross Weight: 0.25lb (133g)

Suggested Use: Take one (1) twice a day as a dietary supplement. For best results, take 20-30 min before a meal with an 8oz glass of water or as directed by your healthcare professional.

Caution: Do not exceed recommended dose. Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Warning: Keep out of reach of children. Do not use if the safety seal is damaged or missing. Store in a cool, dry place.


The Food and Drug Administration has not evaluated these statements. This product is not intended to diagnose, treat, cure, or prevent any disease.

Gluten-free Vegetarian Lactose-free Allergen-free Hormone-free No fillers Vegan friendly Sugar-free

If you’ve been trying to lose weight at any point over the past several years, chances are you’ve heard about, or possibly even tried, a ketogenic diet. This fat-heavy approach to weight loss has gained a lot of attention in recent years, but it’s not the easiest diet to get quite right.


 

Originally developed in the 1920s to help children with difficult-to-control epilepsy, the ketogenic, or keto, diet eliminates nearly all carbohydrates. This means your body has to rely on other means of fuel, such as fat and protein.

The classic keto diet "is a high-fat, adequate-protein, low-carbohydrate diet designed to produce ketosis through mimicking the metabolic changes of starvation, forcing the body to use fat as its primary source of energy," explains Cathy Leman, a dietitian, personal trainer, nutrition therapist and breast cancer survivor based in Chicago. Leman is also the founder and creator of the Peaceful Plate program.

Truly following a classic keto diet means you’ll be taking in 90% of your daily calories from fat. Your protein level should stay below 6% of total calories, and carbohydrates should be kept at 4% of daily calories.


 

Helping the Body Achieve Ketosis

Hitting those ratios is important to make the keto diet work. When the body relies on fat for fuel, it generates ketone bodies, which are chemicals manufactured in the liver when fat is broken down and turned into energy. This process is called ketosis. If you have excess fat in your body, it stands to reason that you should be able to burn that as fuel to help you lose weight, which is why the keto diet is popular.

However, getting into and staying in ketosis can be tricky because it requires consistently consuming that exact ratio of carbs to fats to proteins. Emilie Vandenberg, a registered dietitian at the Ohio State University Wexner Medical Center in Columbus, explains that although the ketogenic diet is often thought of as a low-carb, high-protein diet, eating too much protein can prevent you from entering or maintaining ketosis.


That's where certain substances called exogenous ketogenic supplements – aka keto diet pills – come into play.

 

The human body generates ketone bodies naturally – or endogenously in med-speak – when it breaks down fat for fuel. But you can also introduce ketone bodies from an exogenous – or external – source, such as an exogenous ketogenic supplement.

Essentially, exogenous ketogenic supplements are a pill or powder that contains ketone bodies. These supplements are intended to boost the levels of ketone bodies as a whole in the human body to facilitate ketosis. The idea is that by supplementing exogenous ketones, you may not have to actually eat a keto diet at all to reap the benefits.

Erin Holley, a registered dietitian at the Ohio State University Wexner Medical Center, says, “In theory, taking extra ketones in the diet may help the body lose weight by using ketones for energy and therefore burning fat. The claim is that you can take these keto diet pills and not have to follow a low-carb diet.”


Potential metabolic activities of raspberry ketone

Abstract

Novel food and food compounds interventions have attracted a lot of attention nowadays for the prevention and treatment of metabolic diseases. Raspberry ketone (RK) is aromatic compound found within red fruits and berries, has been used as an over-the-counter product for weight loss. However, actually, the effect of RK on weight loss is still controversial, and the mechanism is largely unknown. Besides, in vivo and in vitro studies have demonstrated the beneficial effect of RK on the development of other metabolic diseases. In this review, we comprehensively highlighted the synthesis, bioavailability, and metabolism of RK, and summarized the progress made in our understanding of the potential biological activities of RK, including antiobesity, antidiabetes, cardioprotection, and hepatoprotection, as well as their underlying mechanisms. This paper provides a critical overview about the current findings and proposes the future studies in the area of RK on human health. PRACTICAL APPLICATIONS: Raspberry ketone (RK) has been used for weight control for years, but this effect is controversial considering food intake. Additionally, RK is beneficial for T2DM, liver and heart injury. The underlying mechanisms of the protective effect of RK including accelerating fatty acid oxidation, balancing serum glucose level, anti-inflammation, antioxidant process, and so on. In this context, we provide a comprehensive analysis of the benefits of RK against many metabolic diseases and discuss the underlying molecular mechanisms. We hope our work will be helpful for further researches on RK and improve its public recognition.

Effect of Garcinia cambogia supplement on obesity indices: A systematic review and dose-response meta-analysis

Abstract

Objective: Several trials have examined the effect of Garcinia cambogia supplement on the weight and body composition, but their results are conflicting. This systematic review and dose-response meta-analysis was designed to determine the effect of Garcinia cambogia supplement on the obesity indices in human randomized controlled trials (RCTs).

Methods: PubMed/Medline, Scopus, Cochrane library, and Web of Science databases were searched up to 1th January, 2020, to screen relevant trials. The mean changes in the weight, body mass index (BMI), percentage of fat mass (PFM), and waist circumference (WC) from the baseline were used to conduct the present dose response meta-analysis.

Results: In the current study, eight trials (including 530 subjects) were included. Garcinia cambogia supplement significantly reduced the weight by -1.34 kg (95% CI: -2.62 to -0.07, P = 0.03), BMI by -0.99 kg/m2 (95% CI: -1.48 to -0.49, P < 0.001), PFM by -0.42% (95% CI: -0.77 to -0.06, P = 0.02), and WC by -4.16 cm (95% CI: -7.83 to -0.49, P = 0.02) compared with the placebo group. Dose-response analysis revealed that there is a nonlinear association between Garcinia cambogia dosage and changes in the body weight (Pnonlinearity = 0.04) and BMI (Pnonlinearity < 0.001) not PFM (Pnonlinearity = 0.68). There was no publication bias among the studies.

Conclusion: Our results suggested that Garcinia cambogia supplement had a significant effect on the body weight, BMI, PFA, and WC as compared with the placebo.

Anti-inflammatory Action of Green Tea

Abstract

Background: Green tea has been shown to have beneficial effects against a variety of diseases such as cancer, obesity, diabetes, cardiovascular disease, and neurodegenerative diseases. Through cellular, animal, and human experiments, green tea and its major component, epigallocatechin-3-gallate (EGCG) have been demonstrated to have anti-inflammatory effects. Our previous findings have indicated that green tea and EGCG suppress the gene and/or protein expression of inflammatory cytokines and inflammation-related enzymes.

Methods: Using bibliographic databases, particularly PubMed (provided by the http://www.ncbi.nlm.nih.gov/pubmed, US National Library of Medicine, National Institutes of Health, United States), we examined the potential usefulness of green tea/EGCG for the prevention and treatment of inflammatory diseases in human clinical and epidemiological studies. We also reviewed results from cellular and animal experiments and proposed action mechanisms.

Results: Most of the results from the human studies indicated the beneficial effects of green tea and tea catechins against inflammatory diseases. The cellular and animal studies also provided evidence for the favorable effects of green tea/EGCG. These results are compatible with our previous findings and can be largely explained by a mechanism wherein green tea/EGCG acts as an antioxidant to scavenge reactive oxygen species, leading to attenuation of nuclear factor-κB activity.

Conclusion: Since green tea and EGCG have multiple targets and act in a pleiotropic manner, we may consider their usage to improve the quality of life in patients with inflammatory disease. Green tea and EGCG have beneficial health effects and no severe adverse effects; however, care should be taken to avoid overdosage, which may induce deleterious effects including hepatic injury.

The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis

Abstract

Background and aim: Cardiovascular disease remains the primary cause of noncommunicable disease- related death. The present systematic review and meta-analysis was performed to assess the possible benefit of the green coffee bean extract on cardio-metabolic markers.

Methods: PubMed, Scopus, Web of Science, and Cochrane Library were systematically searched to identify clinical trials that examined the effect of green coffee bean extract on cardio-metabolic risk factors including serum lipid profiles, glycemic status-related markers, blood pressure, and anthropometric indices. Since the included RCTs were carried out in different settings, random effect models were used to conduct all meta-analyses.

Results: Fifteen studies (19 arms) consisting of 637 participants were included. The results indicated that green coffee bean extract significantly reduced levels of total cholesterol (-5.93 mg/dl; 95% CI: -9.21, -2.65; I2: 0%), fasting plasma glucose (-2.21 mg/dl; 95% CI: -3.94, -0.48; I2: 32%), systolic blood pressure (-3.08 mmHg; 95% CI: -4.41, -1.75; I2: 26%), diastolic blood pressure (-2.27 mmHg; 95% CI: -3.82, -0.72; I2: 61%), body weight (-1.24 kg; 95% CI: -1.82, -0.66; I2: 15%), and BMI (-0.55 kg/m2; 95% CI: -0.88, -0.22; I2: 73%). Although the pooled effect size of LDL-C, fasting insulin, and waist circumstance were significant, the results were significantly influenced by individual studies. No significant effect was detected for triglycerides, HDL-C, HbA1C, and HOMA-IR. However, the nonsignificant pooled effect size for triglyceride levels was influenced by one individual study.

Conclusion: The present study suggests that green coffee been extract consumption can improve total cholesterol, triglycerides, body weight, blood pressure, and fasting plasma glucose.

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